Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
A0A3B3IT33
UPID:
TR51G_HUMAN
Alternative names:
Tripartite motif-containing 51G pseudogene
Alternative UPACC:
A0A3B3IT33
Background:
The Putative tripartite motif-containing protein 51G, also known as Tripartite motif-containing 51G pseudogene, represents a unique segment of the human genome. Its classification as a pseudogene suggests a complex evolutionary history, potentially involving gene duplication, mutation, and functional diversification. The tripartite motif (TRIM) family is known for its involvement in various cellular processes, including intracellular signaling, development, apoptosis, and protein ubiquitination.
Therapeutic significance:
Understanding the role of Putative tripartite motif-containing protein 51G could open doors to potential therapeutic strategies. Its association with the TRIM family hints at significant, yet undiscovered, pathways that may be critical in human disease and health.