Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
A6NGJ6
UPID:
TRI64_HUMAN
Alternative names:
-
Alternative UPACC:
A6NGJ6
Background:
Tripartite motif-containing protein 64, encoded by the gene symbol A6NGJ6, plays a crucial role in cellular processes. Its unique structure, characterized by the tripartite motif, allows it to participate in a wide range of biological functions. This protein's involvement in cellular mechanisms makes it a subject of intense study within the scientific community.
Therapeutic significance:
Understanding the role of Tripartite motif-containing protein 64 could open doors to potential therapeutic strategies. Its pivotal role in cellular processes suggests that targeting this protein could lead to innovative treatments for diseases.