Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
A6NLI5
UPID:
TR64C_HUMAN
Alternative names:
-
Alternative UPACC:
A6NLI5; A0A087WYH8
Background:
Tripartite motif-containing protein 64C plays a crucial role in cellular processes, although its specific functions are yet to be fully elucidated. This protein, encoded by the gene with the accession number A6NLI5, is part of a larger family known for their involvement in various cellular mechanisms.
Therapeutic significance:
Understanding the role of Tripartite motif-containing protein 64C could open doors to potential therapeutic strategies. Its multifaceted role in biological systems makes it an intriguing subject for scientific inquiry, promising advancements in medical treatments.