Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
C9JE40
UPID:
PATL2_HUMAN
Alternative names:
PAT1-like protein 2; Protein PAT1 homolog a
Alternative UPACC:
C9JE40
Background:
Protein PAT1 homolog 2, also known as PAT1-like protein 2 and Protein PAT1 homolog a, plays a crucial role in cellular processes as an RNA-binding protein that acts as a translational repressor. Its involvement in the regulation of RNA stability and translation underscores its importance in cellular homeostasis and developmental processes.
Therapeutic significance:
The protein is directly linked to Oocyte/zygote/embryo maturation arrest 4, an autosomal recessive infertility disorder. This association highlights the protein's critical role in reproductive health, specifically in oocyte maturation and early embryonic development. Understanding the role of Protein PAT1 homolog 2 could open doors to potential therapeutic strategies for treating infertility disorders.