Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
O15235
UPID:
RT12_HUMAN
Alternative names:
28S ribosomal protein S12, mitochondrial; MT-RPS12
Alternative UPACC:
O15235; Q53X98
Background:
Small ribosomal subunit protein uS12m, also known as 28S ribosomal protein S12, mitochondrial (MT-RPS12), plays a crucial role in the mitochondrial ribosome. Its primary function is to ensure the accurate translation of messenger RNA into proteins within the mitochondria, a process vital for cellular energy production and metabolic functions.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS12m could open doors to potential therapeutic strategies. Its pivotal role in protein synthesis within mitochondria suggests that targeting MT-RPS12 could offer new avenues for treating diseases linked to mitochondrial dysfunction.