Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
O94844
UPID:
RHBT1_HUMAN
Alternative names:
-
Alternative UPACC:
O94844
Background:
Rho-related BTB domain-containing protein 1 plays a crucial role in cellular processes, including regulation of cytoskeletal dynamics, gene expression, and cell cycle progression. Its unique structure, characterized by the Rho-related BTB domain, enables it to interact with various molecular partners, facilitating its diverse functions.
Therapeutic significance:
Understanding the role of Rho-related BTB domain-containing protein 1 could open doors to potential therapeutic strategies. Its involvement in fundamental cellular processes makes it a promising target for drug discovery, aiming to modulate its activity for therapeutic benefits.