Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
O95487
UPID:
SC24B_HUMAN
Alternative names:
SEC24-related protein B
Alternative UPACC:
O95487; B7ZKM8; B7ZKN4; Q0VG08
Background:
Protein transport protein Sec24B, also known as SEC24-related protein B, is a crucial component of the COPII complex, facilitating the formation of transport vesicles from the endoplasmic reticulum (ER) to the Golgi complex. It plays a pivotal role in cargo selection, preferentially packaging molecules with specific motifs, indicating its selective nature in cellular transport mechanisms.
Therapeutic significance:
Understanding the role of Protein transport protein Sec24B could open doors to potential therapeutic strategies. Its selective nature in cargo packaging and transport underscores its potential as a target in modulating cellular processes, offering insights into novel therapeutic avenues.