Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
O95837
UPID:
GNA14_HUMAN
Alternative names:
-
Alternative UPACC:
O95837; B1ALW3
Background:
Guanine nucleotide-binding protein subunit alpha-14 plays a pivotal role as a modulator or transducer in various transmembrane signaling systems. These proteins are essential for transmitting signals from the outside to the inside of a cell, thereby influencing cellular responses.
Therapeutic significance:
Understanding the role of Guanine nucleotide-binding protein subunit alpha-14 could open doors to potential therapeutic strategies. Its involvement in signal transduction pathways makes it a key target for drug discovery efforts aimed at modulating cellular processes.