Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
P00709
UPID:
LALBA_HUMAN
Alternative names:
Lactose synthase B protein; Lysozyme-like protein 7
Alternative UPACC:
P00709; Q6FGX0; Q9UDK4
Background:
Alpha-lactalbumin, also known as Lactose synthase B protein or Lysozyme-like protein 7, plays a crucial role in lactose synthesis, the primary carbohydrate in milk. It acts as a regulatory subunit, modifying galactosyltransferase's substrate specificity in the mammary gland to favor glucose, facilitating lactose production. Beyond the mammary gland, it influences glycoprotein formation by transferring galactose onto oligosaccharide chains.
Therapeutic significance:
Understanding the role of Alpha-lactalbumin could open doors to potential therapeutic strategies.