Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
P01215
UPID:
GLHA_HUMAN
Alternative names:
Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; Follicle-stimulating hormone alpha chain; Follitropin alpha chain; Luteinizing hormone alpha chain; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; Thyrotropin alpha chain
Alternative UPACC:
P01215
Background:
The Glycoprotein hormones alpha chain, known by its UniProt accession number P01215, serves as a shared alpha subunit for several key hormones in the human body, including thyrotropin (TSH), lutropin (LH), follitropin (FSH), and choriogonadotropin (CG). These hormones are crucial for a variety of physiological processes, such as thyroid function, reproduction, and metabolism.
Therapeutic significance:
Understanding the role of Glycoprotein hormones alpha chain could open doors to potential therapeutic strategies.