Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We employ our advanced, specialised process to create targeted libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
It includes in-depth molecular simulations of both the catalytic and allosteric binding pockets, with ensemble virtual screening focusing on their conformational flexibility. For modulators, the process includes considering the structural shifts due to reaction intermediates to boost activity and selectivity.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P0C5J1
UPID:
F86B2_HUMAN
Alternative names:
-
Alternative UPACC:
P0C5J1
Background:
Putative protein N-methyltransferase FAM86B2, encoded by the gene with the UniProt accession number P0C5J1, is a member of the FAM86 family. This protein is hypothesized to participate in the methylation of proteins, a critical post-translational modification influencing protein function and cellular processes.
Therapeutic significance:
Understanding the role of Putative protein N-methyltransferase FAM86B2 could open doors to potential therapeutic strategies. Its involvement in protein methylation suggests a fundamental role in cellular mechanisms, which, when elucidated, may offer novel intervention points for drug discovery.