Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
It includes comprehensive molecular simulations of the catalytic and allosteric binding pockets and the ensemble virtual screening accounting for their conformational mobility. In the case of designing modulators, the structural changes induced by reaction intermediates are taken into account to leverage activity and selectivity.
Key features that set our library apart include:
partner
Reaxense
upacc
P15088
UPID:
CBPA3_HUMAN
Alternative names:
Carboxypeptidase A3
Alternative UPACC:
P15088; Q96E94
Background:
Mast cell carboxypeptidase A, also known as Carboxypeptidase A3, is a crucial enzyme encoded by the gene with the accession number P15088. This protein plays a significant role in the breakdown of peptide bonds, specifically removing amino acids from the ends of proteins and peptides. Its activity is essential in various biological processes, including digestion and the modulation of peptide hormone activity.
Therapeutic significance:
Understanding the role of Mast cell carboxypeptidase A could open doors to potential therapeutic strategies. Its involvement in peptide processing suggests its potential impact on diseases related to peptide hormone imbalances and digestive disorders. Exploring its function further could lead to novel treatments for such conditions.