Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
P20337
UPID:
RAB3B_HUMAN
Alternative names:
-
Alternative UPACC:
P20337; Q5VUL2; Q9BSI1
Background:
Ras-related protein Rab-3B plays a crucial role in protein transport, facilitating vesicular traffic within cells. This protein is part of the Rab family, known for its significance in intracellular transport mechanisms.
Therapeutic significance:
Understanding the role of Ras-related protein Rab-3B could open doors to potential therapeutic strategies. Its involvement in cellular transport processes makes it a candidate for research in diseases where these pathways are disrupted.