Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P31641
UPID:
SC6A6_HUMAN
Alternative names:
Solute carrier family 6 member 6
Alternative UPACC:
P31641; B2RNU7; Q9BRI2; Q9BXB0
Background:
The Sodium- and chloride-dependent taurine transporter, also known as Solute carrier family 6 member 6, plays a crucial role in the transport of taurine, beta-alanine, hypotaurine, and GABA. Its activity is essential for maintaining the balance of these compounds in the body, impacting various physiological processes.
Therapeutic significance:
Linked to Hypotaurinemic retinal degeneration and cardiomyopathy, this transporter's dysfunction highlights its potential as a target for therapeutic intervention. Understanding the role of Sodium- and chloride-dependent taurine transporter could open doors to potential therapeutic strategies.