Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P32969
UPID:
RL9_HUMAN
Alternative names:
60S ribosomal protein L9
Alternative UPACC:
P32969
Background:
The Large ribosomal subunit protein uL6, also known as 60S ribosomal protein L9, is a crucial component of the ribosome, identified by its accession number P32969. This protein plays a pivotal role in the ribosome, the cell's protein synthesis machinery, as highlighted in studies (PubMed:23636399, PubMed:32669547). Its involvement in the formation of the large ribosomal subunit underscores its essential function in translating genetic information into functional proteins.
Therapeutic significance:
Understanding the role of Large ribosomal subunit protein uL6 could open doors to potential therapeutic strategies. Its fundamental role in protein synthesis makes it an intriguing target for research, aiming to uncover novel approaches to modulate protein production in various diseases.