Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P46782
UPID:
RS5_HUMAN
Alternative names:
40S ribosomal protein S5
Alternative UPACC:
P46782; B2R4T2; Q96BN0
Background:
The Small ribosomal subunit protein uS7, also known as 40S ribosomal protein S5, plays a crucial role in protein synthesis. As a component of the small ribosomal subunit, it is involved in the intricate process of translating mRNA into polypeptides. This protein is part of the SSU processome, facilitating RNA folding, modifications, and cleavage, essential for the efficient assembly of ribosomal subunits.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS7 could open doors to potential therapeutic strategies. Its pivotal function in protein synthesis makes it a potential target for interventions in diseases where protein production is dysregulated.