Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P56278
UPID:
MTCP1_HUMAN
Alternative names:
Mature T-cell proliferation-1 type B1
Alternative UPACC:
P56278; Q5HYP2
Background:
Protein p13 MTCP-1, also known as Mature T-cell proliferation-1 type B1, plays a crucial role in cellular processes by enhancing the phosphorylation and activation of AKT1 and AKT2. These kinases are key players in cell survival, growth, and proliferation pathways.
Therapeutic significance:
Understanding the role of Protein p13 MTCP-1 could open doors to potential therapeutic strategies. Its involvement in critical signaling pathways highlights its potential as a target for drug discovery efforts aimed at regulating cell growth and survival.