Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
P60866
UPID:
RS20_HUMAN
Alternative names:
40S ribosomal protein S20
Alternative UPACC:
P60866; B2R4F4; B4DW28; P17075; Q5M8S9
Background:
Small ribosomal subunit protein uS10, also known as 40S ribosomal protein S20, is a crucial component of the small ribosomal subunit. It plays a pivotal role in the synthesis of proteins within the cell, as highlighted in research findings (PubMed:23636399). The ribosome, a large ribonucleoprotein complex, is fundamental for translating mRNA into polypeptides, thereby facilitating gene expression.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS10 could open doors to potential therapeutic strategies. Its essential function in protein synthesis makes it a potential target for interventions in diseases where protein synthesis plays a critical role.