Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P62277
UPID:
RS13_HUMAN
Alternative names:
40S ribosomal protein S13
Alternative UPACC:
P62277; B2R549; P19116; Q02546; Q29200; Q498Y0
Background:
The Small ribosomal subunit protein uS15, also known as 40S ribosomal protein S13, plays a crucial role in protein synthesis. As a component of the small ribosomal subunit, it is integral to the ribosome's function in translating mRNA into polypeptides. This protein is part of the SSU processome, facilitating RNA folding, modifications, and cleavage, essential for the efficient production of proteins within the cell.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS15 could open doors to potential therapeutic strategies. Its pivotal function in protein synthesis makes it a potential target for interventions in diseases where protein production is dysregulated.