Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P82914
UPID:
RT15_HUMAN
Alternative names:
28S ribosomal protein S15, mitochondrial
Alternative UPACC:
P82914; B2RD82; Q9H2K1
Background:
The Small ribosomal subunit protein uS15m, also known as 28S ribosomal protein S15, mitochondrial, plays a crucial role in the mitochondrial ribosome. It is involved in the synthesis of proteins within the mitochondria, a process essential for cellular energy production and metabolic functions. The protein's unique structure and function within the mitochondrial ribosome make it a subject of interest for understanding mitochondrial biology and its impact on cellular health.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS15m could open doors to potential therapeutic strategies. Its critical function in protein synthesis within mitochondria highlights its importance in cellular metabolism and energy production, suggesting that targeting this protein could offer new avenues for treating diseases related to mitochondrial dysfunction.