Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q07654
UPID:
TFF3_HUMAN
Alternative names:
Intestinal trefoil factor; Polypeptide P1.B
Alternative UPACC:
Q07654; A0A0A6YYJ4; E9PBB5; Q96NX0; Q9UDA5
Background:
Trefoil factor 3, also known as Intestinal trefoil factor and Polypeptide P1.B, plays a crucial role in the maintenance and repair of the intestinal mucosa. It is instrumental in promoting the mobility of epithelial cells during healing processes, acting as a motogen.
Therapeutic significance:
Understanding the role of Trefoil factor 3 could open doors to potential therapeutic strategies. Its pivotal function in epithelial cell mobility and intestinal mucosa repair highlights its therapeutic potential in gastrointestinal diseases.