Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q15404
UPID:
RSU1_HUMAN
Alternative names:
-
Alternative UPACC:
Q15404; A8KA46; D3DRU3; Q6FI17
Background:
Ras suppressor protein 1, identified by the accession number Q15404, plays a crucial role in the Ras signal transduction pathway. This protein is known for its ability to suppress v-Ras transformation in vitro, highlighting its potential impact on cellular signaling and growth regulation.
Therapeutic significance:
Understanding the role of Ras suppressor protein 1 could open doors to potential therapeutic strategies. Its involvement in the Ras pathway suggests a significant potential for targeting in cancer therapy, where Ras signaling is often dysregulated.