Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q16384
UPID:
SSX1_HUMAN
Alternative names:
Cancer/testis antigen 5.1; Synovial sarcoma, X breakpoint 1
Alternative UPACC:
Q16384; A3KN76; Q08AJ2; Q5JQ64
Background:
Protein SSX1, also known as Cancer/testis antigen 5.1 and Synovial sarcoma, X breakpoint 1, plays a pivotal role in transcription modulation and spermatogenesis. Its involvement in these critical biological processes underscores its significance in cellular function and development.
Therapeutic significance:
Linked to Spermatogenic failure, X-linked, 5, a disorder causing male infertility through reduced sperm motility and morphological abnormalities, SSX1's role in disease highlights its potential as a target for therapeutic intervention.