Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q16540
UPID:
RM23_HUMAN
Alternative names:
39S ribosomal protein L23, mitochondrial; L23 mitochondrial-related protein; Ribosomal protein L23-like
Alternative UPACC:
Q16540; A8MT29; Q96Q71
Background:
The Large ribosomal subunit protein uL23m, also known as 39S ribosomal protein L23, mitochondrial, L23 mitochondrial-related protein, and Ribosomal protein L23-like, plays a crucial role in the mitochondrial ribosome. Its involvement in protein synthesis within the mitochondria underscores its importance in cellular energy metabolism and overall cellular function.
Therapeutic significance:
Understanding the role of Large ribosomal subunit protein uL23m could open doors to potential therapeutic strategies. Its pivotal role in mitochondrial function makes it a key target for research aimed at addressing mitochondrial diseases and disorders related to cellular energy metabolism.