Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
This approach involves comprehensive molecular simulations of the catalytic and allosteric binding pockets and ensemble virtual screening that accounts for their conformational flexibility. In the case of designing modulators, the structural adjustments caused by reaction intermediates are considered to improve activity and selectivity.
Key features that set our library apart include:
partner
Reaxense
upacc
Q17R31
UPID:
TATD3_HUMAN
Alternative names:
-
Alternative UPACC:
Q17R31; A6NGS3; B7Z1C1; B7Z978; B7ZLQ6; E9PJE5; E9PNH3; G3V151; Q4G0L1
Background:
Putative deoxyribonuclease TATDN3 plays a crucial role in DNA metabolism, facilitating the breakdown of DNA molecules. This enzyme's activity is essential for DNA repair, replication, and recombination processes, ensuring genomic stability and proper cell function.
Therapeutic significance:
Understanding the role of Putative deoxyribonuclease TATDN3 could open doors to potential therapeutic strategies. Its involvement in DNA metabolism highlights its potential as a target for developing treatments aimed at enhancing DNA repair mechanisms, crucial for combating genetic disorders and improving cell therapy outcomes.