Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q5JU69
UPID:
TOR2A_HUMAN
Alternative names:
Torsin family 2 member A; Torsin-related protein 1
Alternative UPACC:
Q5JU69; A4FU12; A4FU13; Q3ZCN9; Q3ZCP0; Q5JU68; Q66K87; Q6UXW6; Q8NAN5; Q96SL7
Background:
Torsin family 2 member A, also known as Torsin-2A and Torsin-related protein 1, plays a crucial role in cellular processes. Its unique structure and alternative names highlight its significance in the biological system. The specific functions of Torsin-2A, while not fully elucidated, are pivotal to understanding cellular dynamics.
Therapeutic significance:
Understanding the role of Torsin-2A could open doors to potential therapeutic strategies. Its multifaceted role in biological systems makes it an intriguing subject for scientific inquiry, promising advancements in medical research and drug discovery.