Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q5TFG8
UPID:
ZC21B_HUMAN
Alternative names:
-
Alternative UPACC:
Q5TFG8; B2RUZ7; Q5TFG9
Background:
Zinc finger C2HC domain-containing protein 1B plays a crucial role in cellular processes through its involvement in DNA binding and gene expression regulation. Its unique zinc finger motif enables specific interactions with DNA, contributing to the intricate control of genetic information flow.
Therapeutic significance:
Understanding the role of Zinc finger C2HC domain-containing protein 1B could open doors to potential therapeutic strategies. Its pivotal function in gene regulation makes it a promising target for interventions in diseases where gene expression is disrupted.