Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q5W111
UPID:
SPRY7_HUMAN
Alternative names:
Chronic lymphocytic leukemia deletion region gene 6 protein
Alternative UPACC:
Q5W111; A8K3G1; O60648; Q8TBG8; Q96T69
Background:
The SPRY domain-containing protein 7, also known as Chronic lymphocytic leukemia deletion region gene 6 protein, is a notable entity in the realm of molecular biology. Its unique structure, characterized by the SPRY domain, suggests a specialized role in cellular processes. This protein's involvement in intricate cellular mechanisms underscores its potential as a key player in biological systems.
Therapeutic significance:
Understanding the role of SPRY domain-containing protein 7 could open doors to potential therapeutic strategies. Its association with cellular functions highlights its importance in maintaining cellular integrity and presents an opportunity for targeted drug discovery efforts.