Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q6T311
UPID:
ARL9_HUMAN
Alternative names:
-
Alternative UPACC:
Q6T311
Background:
ADP-ribosylation factor-like protein 9 (ARL9) plays a crucial role in cellular processes, including vesicle trafficking and cytoskeleton organization. Its precise molecular mechanisms and interactions within the cell remain a subject of active research. ARL9's involvement in these fundamental cellular functions suggests its importance in maintaining cellular homeostasis and integrity.
Therapeutic significance:
Understanding the role of ADP-ribosylation factor-like protein 9 could open doors to potential therapeutic strategies. While direct links to specific diseases are yet to be established, the protein's fundamental role in cellular processes positions it as a potential target for therapeutic intervention in disorders related to cellular trafficking and organization.