Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q86XD8
UPID:
ZFAN4_HUMAN
Alternative names:
AN1-type zinc finger and ubiquitin domain-containing protein-like 1
Alternative UPACC:
Q86XD8; A8K8V4; B2RAX2; Q5VVY5
Background:
AN1-type zinc finger protein 4, alternatively known as AN1-type zinc finger and ubiquitin domain-containing protein-like 1, plays a crucial role in cellular processes through its involvement in ubiquitin-mediated protein degradation pathways. Its unique structure, characterized by the presence of AN1-type zinc finger domains, suggests a specialized function in protein-protein interactions.
Therapeutic significance:
Understanding the role of AN1-type zinc finger protein 4 could open doors to potential therapeutic strategies. Its involvement in protein degradation pathways highlights its importance in maintaining cellular homeostasis and presents an opportunity for targeted drug discovery efforts.