Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q86YG4
UPID:
NT5D4_HUMAN
Alternative names:
-
Alternative UPACC:
Q86YG4
Background:
The 5'-nucleotidase domain-containing protein 4, identified by its unique accession number Q86YG4, plays a crucial role in nucleotide metabolism. This protein is involved in the hydrolysis of nucleotides to nucleosides, a fundamental process in the cellular energy transfer and signaling pathways. Its specific functions and interactions within the cell offer a rich field for exploration, given its potential involvement in key biological processes.
Therapeutic significance:
Understanding the role of 5'-nucleotidase domain-containing protein 4 could open doors to potential therapeutic strategies. While direct associations with diseases are yet to be established, the protein's fundamental role in nucleotide metabolism suggests its potential impact on conditions related to energy transfer and cellular signaling. Investigating this protein could lead to novel insights into metabolic disorders and pave the way for innovative treatments.