Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our top-notch dedicated system is used to design specialised libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
This approach involves comprehensive molecular simulations of the catalytic and allosteric binding pockets and ensemble virtual screening that accounts for their conformational flexibility. In the case of designing modulators, the structural adjustments caused by reaction intermediates are considered to improve activity and selectivity.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8IXN7
UPID:
RIMKA_HUMAN
Alternative names:
N-acetylaspartylglutamylglutamate synthase A; Ribosomal protein S6 modification-like protein A
Alternative UPACC:
Q8IXN7; Q5VUS5
Background:
N-acetylaspartylglutamate synthase A, also known as N-acetylaspartylglutamylglutamate synthase A and Ribosomal protein S6 modification-like protein A, plays a crucial role in the synthesis of N-acetyl-L-aspartyl-L-glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate. These compounds are vital for various neurological processes.
Therapeutic significance:
Understanding the role of N-acetylaspartylglutamate synthase A could open doors to potential therapeutic strategies. Its involvement in the synthesis of key neurological compounds highlights its importance in neuroscientific research and drug discovery.