Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q8N0S2
UPID:
SYCE1_HUMAN
Alternative names:
Cancer/testis antigen 76
Alternative UPACC:
Q8N0S2; B2RC80; Q9BWU3; Q9BWU4
Background:
Synaptonemal complex central element protein 1, also known as Cancer/testis antigen 76, plays a pivotal role in meiosis, a process critical for sexual reproduction. It is a major component of the transverse central element of synaptonemal complexes (SCS), which form between homologous chromosomes during meiotic prophase. Its presence is essential for the incorporation into the central element, suggesting a significant role in synaptonemal complex assembly, stabilization, and recombination.
Therapeutic significance:
The protein's involvement in Premature ovarian failure 12 and Spermatogenic failure, 15, conditions affecting fertility, underscores its potential as a target for therapeutic intervention. Understanding the role of Synaptonemal complex central element protein 1 could open doors to potential therapeutic strategies for these reproductive disorders.