Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
It includes in-depth molecular simulations of both the catalytic and allosteric binding pockets, with ensemble virtual screening focusing on their conformational flexibility. For modulators, the process includes considering the structural shifts due to reaction intermediates to boost activity and selectivity.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q8N7N1
UPID:
F86B1_HUMAN
Alternative names:
-
Alternative UPACC:
Q8N7N1
Background:
Putative protein N-methyltransferase FAM86B1, encoded by the gene with the accession number Q8N7N1, plays a crucial role in the methylation process, a fundamental biochemical reaction that affects protein function and regulation. Despite its significance, the specific functions and mechanisms of action of FAM86B1 remain to be fully elucidated.
Therapeutic significance:
Understanding the role of Putative protein N-methyltransferase FAM86B1 could open doors to potential therapeutic strategies. Its involvement in methylation processes suggests a broad impact on cellular functions, making it an intriguing subject for scientific inquiry and drug discovery efforts.