Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We utilise our cutting-edge, exclusive workflow to develop focused libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
The procedure entails thorough molecular simulations of the catalytic and allosteric binding pockets, accompanied by ensemble virtual screening that factors in their conformational flexibility. When developing modulators, the structural modifications brought about by reaction intermediates are factored in to optimize activity and selectivity.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8NCT3
UPID:
MACA2_HUMAN
Alternative names:
-
Alternative UPACC:
Q8NCT3; B4DF35; B7ZLT4; B9EGB9; O94969; Q0VGC1; Q7Z4L2
Background:
The Putative tyrosine carboxypeptidase MATCAP2 plays a crucial role in protein processing, specifically in the modification of tyrosine residues. This enzyme's activity is pivotal for the proper functioning of various biological processes, including signal transduction and cellular communication.
Therapeutic significance:
Understanding the role of Putative tyrosine carboxypeptidase MATCAP2 could open doors to potential therapeutic strategies. Its involvement in key biological processes makes it a promising target for drug discovery, aiming to modulate its activity for therapeutic benefits.