Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q92688
UPID:
AN32B_HUMAN
Alternative names:
Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; Silver-stainable protein SSP29
Alternative UPACC:
Q92688; B2R9C7; O00655; P78458; P78459
Background:
Acidic leucine-rich nuclear phosphoprotein 32 family member B, also known as Acidic protein rich in leucines, Putative HLA-DR-associated protein I-2, and Silver-stainable protein SSP29, plays a pivotal role in cell biology. It is involved in cell proliferation, apoptosis, cell cycle progression, and transcription regulation. This protein also exhibits histone chaperone properties, influencing the transcription of specific genes and is crucial in the nucleocytoplasmic transport of specific mRNAs. Additionally, it has a significant role in adaptive immune responses and mRNA expression.
Therapeutic significance:
Understanding the role of Acidic leucine-rich nuclear phosphoprotein 32 family member B could open doors to potential therapeutic strategies.