Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q96FN4
UPID:
CPNE2_HUMAN
Alternative names:
Copine II
Alternative UPACC:
Q96FN4; Q68D19; Q719H8; Q86XP9
Background:
Copine-2, also known as Copine II, is a calcium-dependent phospholipid-binding protein that plays a crucial role in calcium-mediated intracellular processes. It is characterized by its ability to bind to cell membranes in a calcium-dependent manner, indicating its involvement in various cellular functions and signaling pathways.
Therapeutic significance:
Understanding the role of Copine-2 could open doors to potential therapeutic strategies. Its involvement in calcium-mediated processes suggests its potential impact on cellular functions, making it a target for research in disease mechanisms and drug discovery.