Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9BRT3
UPID:
MIEN1_HUMAN
Alternative names:
HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; Protein C35
Alternative UPACC:
Q9BRT3
Background:
Migration and invasion enhancer 1, also known as HBV X-transactivated gene 4 protein, HBV XAg-transactivated protein 4, and Protein C35, plays a pivotal role in cellular processes. It enhances cell migration by promoting filopodia formation at the leading edge of migrating cells, regulates apoptosis potentially through CASP3 control, and may participate in redox-related processes.
Therapeutic significance:
Understanding the role of Migration and invasion enhancer 1 could open doors to potential therapeutic strategies.