Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q9C0H2
UPID:
TTYH3_HUMAN
Alternative names:
-
Alternative UPACC:
Q9C0H2; A4D201; B7WP98; Q6L749; Q6ZVG3; Q8TEG6
Background:
Protein tweety homolog 3 is identified as a probable large-conductance Ca(2+)-activated chloride channel, playing a pivotal role in calcium signal transduction. This protein's unique function highlights its importance in cellular processes, where calcium ions act as a universal signal leading to various physiological responses.
Therapeutic significance:
Understanding the role of Protein tweety homolog 3 could open doors to potential therapeutic strategies. Its involvement in calcium signal transduction suggests a foundational role in cellular physiology, offering a promising avenue for drug discovery aimed at modulating calcium-dependent pathways.