Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9H169
UPID:
STMN4_HUMAN
Alternative names:
Stathmin-like protein B3
Alternative UPACC:
Q9H169; B7Z2Z7; B7Z4I9; D3DSS8; D3DSS9; G5EA16; Q2TAB9
Background:
Stathmin-4, also known as Stathmin-like protein B3, plays a crucial role in cellular processes by exhibiting microtubule-destabilizing activity. This activity is vital for the regulation of microtubule dynamics, which is essential for cell division, intracellular transport, and cell motility.
Therapeutic significance:
Understanding the role of Stathmin-4 could open doors to potential therapeutic strategies. Its pivotal function in microtubule dynamics suggests that modulating its activity could have implications for treating diseases where cell division is dysregulated.