Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9NP95
UPID:
FGF20_HUMAN
Alternative names:
-
Alternative UPACC:
Q9NP95; B2RPH5
Background:
Fibroblast growth factor 20 (FGF20) plays a pivotal role in central nervous system development and function. Its involvement in neurotrophic activities underscores its importance in neural health and disease.
Therapeutic significance:
FGF20's link to Renal hypodysplasia/aplasia 2, a severe kidney development disorder, highlights its potential as a target for therapeutic intervention. Understanding the role of Fibroblast growth factor 20 could open doors to potential therapeutic strategies.