Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9NW82
UPID:
WDR70_HUMAN
Alternative names:
-
Alternative UPACC:
Q9NW82; Q9H053
Background:
WD repeat-containing protein 70, identified by its accession number Q9NW82, plays a crucial role in cellular processes through its involvement in protein-protein interactions. The WD repeat, a conserved motif, facilitates the assembly of protein complexes, indicating its significance in cellular function and signaling pathways.
Therapeutic significance:
Understanding the role of WD repeat-containing protein 70 could open doors to potential therapeutic strategies. Its pivotal role in protein assembly and signaling pathways makes it a target of interest in drug discovery, aiming to modulate its function for therapeutic benefits.