Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q9UJJ7
UPID:
RUSD1_HUMAN
Alternative names:
Ribosomal large subunit pseudouridine synthase C-like protein
Alternative UPACC:
Q9UJJ7; D3DU66
Background:
RNA pseudouridylate synthase domain-containing protein 1, also known as Ribosomal large subunit pseudouridine synthase C-like protein, plays a crucial role in the modification of RNA. This protein is involved in the synthesis of pseudouridine, a modification that contributes to the stability and function of RNA molecules.
Therapeutic significance:
Understanding the role of RNA pseudouridylate synthase domain-containing protein 1 could open doors to potential therapeutic strategies. Its involvement in RNA stability and function highlights its importance in cellular processes and disease mechanisms.