Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9Y225
UPID:
RNF24_HUMAN
Alternative names:
-
Alternative UPACC:
Q9Y225; D3DVZ2; D3DVZ3; Q9UMH1
Background:
RING finger protein 24, identified by the accession number Q9Y225, is implicated in the intricate process of TRPCs intracellular trafficking. This protein's role, although not fully delineated, is crucial for the proper functioning and regulation of transient receptor potential channels, which are integral to cellular calcium signaling pathways.
Therapeutic significance:
Understanding the role of RING finger protein 24 could open doors to potential therapeutic strategies. Its involvement in the regulation of calcium signaling pathways suggests a foundational role in cellular functions, which, when further explored, could reveal novel targets for drug discovery and development.