Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9Y291
UPID:
RT33_HUMAN
Alternative names:
28S ribosomal protein S33, mitochondrial
Alternative UPACC:
Q9Y291
Background:
Small ribosomal subunit protein mS33, also known as 28S ribosomal protein S33, mitochondrial, plays a crucial role in the mitochondrial ribosome. It is part of the small ribosomal subunit and is involved in the synthesis of proteins within mitochondria, essential for cellular energy production and metabolic processes.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein mS33 could open doors to potential therapeutic strategies. Its involvement in mitochondrial protein synthesis positions it as a key player in cellular metabolism and energy production, areas critical to the health and function of cells.