Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q9Y5W9
UPID:
SNX11_HUMAN
Alternative names:
-
Alternative UPACC:
Q9Y5W9; B3KRL6; B4DPY5; D3DTV0; Q53YC0; Q9H885
Background:
Sorting nexin-11, a phosphoinositide-binding protein, plays a crucial role in protein sorting and membrane trafficking within endosomes. This protein is pivotal in maintaining cellular homeostasis and facilitating the precise delivery of proteins to their destined locations.
Therapeutic significance:
Understanding the role of Sorting nexin-11 could open doors to potential therapeutic strategies. Its involvement in critical cellular processes underscores its potential as a target for therapeutic intervention in diseases where protein sorting and membrane trafficking are compromised.