Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
A8MWK0
UPID:
FS2P1_HUMAN
Alternative names:
Fatty acid desaturase 2 pseudogene 1; Fatty acid desaturase 2B, pseudogene
Alternative UPACC:
A8MWK0
Background:
The Putative fatty acid desaturase 2-like protein FADS2B, also known as Fatty acid desaturase 2 pseudogene 1 and Fatty acid desaturase 2B, pseudogene, plays a crucial role in the biosynthesis of polyunsaturated fatty acids. These enzymes are pivotal in cellular processes, influencing membrane structure, signaling pathways, and metabolic functions.
Therapeutic significance:
Understanding the role of Putative fatty acid desaturase 2-like protein FADS2B could open doors to potential therapeutic strategies. Its involvement in the biosynthesis of essential fatty acids suggests a foundational role in maintaining cellular health and preventing disease.