Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
O75578
UPID:
ITA10_HUMAN
Alternative names:
-
Alternative UPACC:
O75578; B2RAM4; B2RTV5; Q6UXJ6; Q9UHZ8
Background:
Integrin alpha-10, encoded by the gene with the accession number O75578, plays a pivotal role in cellular functions by serving as a receptor for collagen. This protein is part of the integrin family, which is known for mediating cell-cell and cell-extracellular matrix interactions. Integrin alpha-10's specific interaction with collagen highlights its importance in cellular adhesion, migration, and signaling pathways.
Therapeutic significance:
Understanding the role of Integrin alpha-10 could open doors to potential therapeutic strategies. Its involvement in cellular adhesion and signaling pathways makes it a promising target for modulating cell behavior in various medical conditions, potentially leading to breakthroughs in treatment methods.