Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q2NL82
UPID:
TSR1_HUMAN
Alternative names:
-
Alternative UPACC:
Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6
Background:
Pre-rRNA-processing protein TSR1 homolog plays a crucial role in the maturation of the 40S ribosomal subunit within the nucleolus. This protein is essential for the proper assembly and function of ribosomes, which are the cellular machines responsible for protein synthesis.
Therapeutic significance:
Understanding the role of Pre-rRNA-processing protein TSR1 homolog could open doors to potential therapeutic strategies. Its pivotal function in ribosome assembly highlights its importance in cellular biology and disease mechanisms.