Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q86TJ2
UPID:
TAD2B_HUMAN
Alternative names:
ADA2-like protein beta
Alternative UPACC:
Q86TJ2; A0AUJ8; A4QMR7; B3KSN0; B3KU86; Q6MZG9
Background:
Transcriptional adapter 2-beta, also known as ADA2-like protein beta, plays a crucial role in gene expression by coactivating PAX5-dependent transcription in conjunction with SMARCA4 or GCN5L2. This protein's involvement in the regulation of transcription highlights its importance in cellular processes and gene regulation mechanisms.
Therapeutic significance:
Understanding the role of Transcriptional adapter 2-beta could open doors to potential therapeutic strategies. Its pivotal function in transcriptional regulation suggests that modulating its activity could influence gene expression patterns involved in various diseases.